Ventilator associated pneumonia: mechanisms, an appraisal of current therapies and the role for inhaled antibiotics in prevention and treatment ScienceDirect VAP (Ventilator Associated Pneumonia) Explained Simply for Nurses Ventilator Associated Pneumonia (VAP) is a serious hospital acquired infection that develops 48 hours or more after mechanical ventilation. It significantly increases ICU stay Guidelines for the prevention of ventilator associated pneumonia and their implementation. The Spanish Zero VAP bundle Medicina Intensiva Study population profile. ICU = intensive care unit; VAP = Download Scientific Diagram Flow chart of the study. ICU: Intensive care unit; VAP: Download Scientific Diagram